Date published: 2025-9-8

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Anticorps SmcX (F-12): sc-373935

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Fiches techniques
  • L'Anticorps SmcX (F-12) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 1462-1560 situés au niveau C-terminus de SmcX d'origine human
  • recommandé pour la détection de SmcX d'origine human par WB, IP, IF et ELISA
  • Réactifs TransCruz pour une application en ChIP (sc-373935 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SmcX (F-12) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SmcX (F-12)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    SmcX, also known as JARID1C (jumonji, AT rich interactive domain 1C), MRXJ, KDM5C or XE169, is a nuclear protein that contains one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers and belongs to the JARID1 histone demethylase family. Expressed ubiquitously with highest expression in brain and skeletal muscle, SmcX functions as a histone demethylase that removes methyl groups from lysine residues on Histone H3, thereby playing a role in the histone code, as well as transcriptional regulation and chromatin remodeling. SmcX binds iron and α-ketoglutarate as cofactors and can recruit histone deacetylases to neuron silencer elements, thus repressing the transcription of neuronal genes. Defects in the gene encoding SmcX are associated with X-linked mental retardation (XLMR), a condition characterized by cognitive impairment and a low IQ. Multiple isoforms of SmcX are expressed due to alternative splicing events.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps SmcX (F-12)

    sc-373935
    200 µg/ml
    $316.00

    SmcX (F-12): m-IgG Fc BP-HRP Kit

    sc-537888
    200 µg Ab; 10 µg BP
    $354.00

    SmcX (F-12): m-IgGκ BP-HRP Kit

    sc-535343
    200 µg Ab; 40 µg BP
    $354.00

    SmcX (F-12): m-IgG2a BP-HRP Kit

    sc-548137
    200 µg Ab; 10 µg BP
    $354.00

    Anticorps SmcX (F-12) X

    sc-373935 X
    200 µg/0.1 ml
    $316.00

    What is the recommended starting dilution for Western blot for SmcX (F-12): sc-373935 monoclonal antibody?

    Posée par: Cweed
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-373935.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
    Répondue par: Technical Support
    Date de publication: 2017-02-28
    • y_2025, m_8, d_29, h_8CST
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    Rated 5 de 5 de par Great Western blot data of SmcX expression in nonGreat Western blot data of SmcX expression in non-transfected and human SmcX transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-12-18
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    Anticorps SmcX (F-12) est évalué 5.0 de 5 de 1.
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