Anticorps SLUG (C-7): sc-166902
- L'Anticorps SLUG (C-7) est un monoclonal de souris IgG2a κ, cité dans 10 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 71-88 au niveau d'une région interne de SLUG d'origine human
- recommandé pour la détection de SLUG d'origine mouse, rat et human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-166902 X, 200 µg/0.1 ml)
- Voir SLUG (A-7): sc-166476 pour d'autres anticorps conjugués SLUG, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SLUG (C-7) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SLUG (C-7)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The SNAIL family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1 (the human homolog of Drosophila SNAIL) and Smuc. SNAI 1 and SLUG are expressed in placenta and in adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. The SNAIL-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription. Smuc preferentially associates with CAGGTG and CACCTG E-box motifs (CANNTG) on DNA and involves the five putative DNA-binding zinc finger domains at the C-terminal region of Smuc.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SLUG (C-7) | sc-166902 | 200 µg/ml | $316.00 | |||
SLUG (C-7): m-IgG Fc BP-HRP Kit | sc-537543 | 200 µg Ab; 10 µg BP | $354.00 | |||
SLUG (C-7): m-IgGκ BP-HRP Kit | sc-534841 | 200 µg Ab; 40 µg BP | $354.00 | |||
SLUG (C-7): m-IgG2a BP-HRP Kit | sc-548048 | 200 µg Ab; 10 µg BP | $354.00 | |||
SLUG (C-7) peptide neutralisant | sc-166902 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps SLUG (C-7) X | sc-166902 X | 200 µg/0.1 ml | $316.00 |