Date published: 2025-9-9

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Anticorps SKAP (F-11): sc-514112

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Fiches techniques
  • L'anticorps SKAP F-11 est un monoclonal IgM κ L'Anticorps SKAP, cité dans 1 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 81-106 au niveau d'une région interne de SKAP d'origine mouse
  • recommandé pour la détection de SKAP d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Contactez notre Service Technique (ou votre Distributeur local) pour plus d'informations pour recevoir un échantillon GRATUIT de 10 µg de SKAP (F-11): sc-514112.
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SKAP (F-11). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

SKAP Antibody (F-11) is an IgM κ mouse monoclonal SKAP antibody (also designated SKAP antibody) that detects the SKAP protein of mouse, rat and human origin by WB, IP, IF and ELISA. SKAP Antibody (F-11) is available as the non-conjugated anti-SKAP antibody. Interactions between kinetochore and spindle microtubules play a critical role in chromosome segregation during mitosis. SKAP (small kinetochore associated protein), also known as KNSTRN (kinetochore-localized astrin/SPAG5 binding protein), HSD11, C15orf23 or TRAF4AF1, is a 316 widely expressed nuclear and cytoplasmic protein that is an essential component of the mitotic spindle. Required for chromosome alignment during mitosis, SKAP regulates metaphase-to-anaphase transition, promotes normal timing of sister chromatid segregation and maintains spindle pole architecture. SKAP forms a complex with SPAG5 localizes to microtubule ends and stabilizes microtubule-kinetochore attachments. Mutations in the gene encoding SKAP may lead to cutaneous squamous cell carcinomas, a malignancy of the skin. SKAP is encoded by a gene located on human chromosome 15q15.1 and exists as three alternatively spliced isoforms. SKAP is down-regulated by nitric oxide.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps SKAP (F-11)

sc-514112
200 µg/ml
$316.00

SKAP (F-11) peptide neutralisant

sc-514112 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-514112 P appropriate for?

Posée par: Trav11
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-03-01
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Rated 5 de 5 de par Produced positive Western Blot data of D2Ertd750eProduced positive Western Blot data of D2Ertd750e expression in RAW 264.7, F9, CSMLO and NIH/3T3 whole cell lysates and IMR-32 and NIH/3T3 nuclear extracts. -SCBT QC
Date de publication: 2013-03-02
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Anticorps SKAP (F-11) est évalué 5.0 de 5 de 1.
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