Date published: 2025-9-8

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Anticorps Siglec-5/14 (C-2): sc-374584

5.0(1)
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Fiches techniques
  • L'Anticorps Siglec-5/14 (C-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique pour un épitope situé entre les acides aminés 135-173 dans un domaine extracellulaire de Siglec-5 de human
  • recommandé pour la détection de Siglec-5 and Siglec-14 d'origine human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Siglec-5/14 Antibody (C-2) for WB applications. Ces réactifs sont désormais proposés en lots avec Siglec-5/14 Antibody (C-2)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Two families of mammalian lectin-like adhesion molecules bind glycoconjugate ligands in a sialic acid-dependent manner: the selectins and the sialoadhesins. The sialic acid-binding immunoglobulin superfamily lectins, designated siglecs or sialoadhesins, are immunoglobulin superfamily members recognizing sialylated ligands. Siglec-5 binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. There exist four isoforms of hSiglec-5 possessing three (hSiglec-5-3L and -3C) or four (hSiglec-5-4L and -4S) extracellular domains linked to long (hSiglec-5-3L and -4L) or short (hSiglec-5-4S) cytoplasmic tails or existing as a soluble isoform (hSiglec-5-3C). Siglec-5 is expressed by monocytes and neutrophils, but is absent from leukemic cell lines representing early stages of myelomonocytic differentiation. Siglec-5 may play a role in the diagnosis and monitoring of acute myeloid leukemia (AML). Siglec-14 is predominantly expressed in hematopoietic tissues but is also found in lung and testis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps Siglec-5/14 (C-2)

    sc-374584
    200 µg/ml
    $316.00

    Siglec-5/14 (C-2): m-IgG Fc BP-HRP Kit

    sc-540481
    200 µg Ab; 10 µg BP
    $354.00

    Siglec-5/14 (C-2): m-IgG1 BP-HRP Kit

    sc-542151
    200 µg Ab; 20 µg BP
    $354.00

    Siglec-5/14 (C-2) peptide neutralisant

    sc-374584 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-374584 P appropriate for?

    Posée par: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-28
    • y_2025, m_9, d_7, h_4CST
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    Rated 5 de 5 de par Nice Western blot data of SiglecNice Western blot data of Siglec-5 expression in non-transfected and human Siglec-5 transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2013-07-12
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    Anticorps Siglec-5/14 (C-2) est évalué 5.0 de 5 de 1.
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