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SESN2, also known as sestrin 2, HI95, SES2 or SEST2, is a 480 amino acid protein that belongs to the sestrin family of PA26-related proteins. Expressed in a variety of tissues throughout the body, SESN2 is thought to be involved in the regulation of cell growth and survival and may play a role in mediating stress-induced cellular responses. SESN2 expression is upregulated following oxidative stress or DNA damage. This leads to cell toxicity and subsequent apoptosis, implying an essential role for SESN2 in the regulation of cell viability. Conversely, overexpression of SESN2 in breast cancer cells leads to protection from apoptosis, suggesting a possible role for SESN2 in tumor progression. SESN2 is, therefore, a crucial regulator of cell survival whose function varies depending on cellular conditions.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SESN2 (F-1) | sc-514058 | 200 µg/ml | $316.00 | |||
SESN2 (F-1): m-IgG Fc BP-HRP Kit | sc-538577 | 200 µg Ab; 10 µg BP | $354.00 | |||
SESN2 (F-1): m-IgGκ BP-HRP Kit | sc-536215 | 200 µg Ab; 40 µg BP | $354.00 | |||
SESN2 (F-1): m-IgG1 BP-HRP Kit | sc-545777 | 200 µg Ab; 20 µg BP | $354.00 | |||
SESN2 (F-1) peptide neutralisant | sc-514058 P | 100 µg/0.5 ml | $68.00 |