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Proteoglycans stored in the secretory granules of many hematopoietic cells contain a protease-resistant peptide core that may be important for neutralizing hydrolytic enzymes. Serglycin is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Serglycin is a chondroitin sulfate-bearing proteoglycan that functions in the transport of cationic granular proteins. The immune system relies on granule exocytosis as the main pathway for elimination of virus-infected cells and tumor cells by cytotoxic T lymphocytes and natural killer cells, thus indicating an important role for serglycin in normal immune function.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
LI-COR® et Odyssey® sont marques déposées de LI-COR Biosciences
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Serglycin (H-9) | sc-393521 | 200 µg/ml | $316.00 | |||
Serglycin (H-9): m-IgG Fc BP-HRP Kit | sc-538235 | 200 µg Ab; 10 µg BP | $354.00 | |||
Serglycin (H-9): m-IgGκ BP-HRP Kit | sc-535808 | 200 µg Ab; 40 µg BP | $354.00 | |||
Serglycin (H-9): m-IgG2b BP-HRP Kit | sc-549929 | 200 µg Ab; 10 µg BP | $354.00 | |||
Serglycin (H-9) peptide neutralisant | sc-393521 P | 100 µg/0.5 ml | $68.00 |