Anticorps Septin 10 (C-3): sc-365776
- L'Anticorps Septin 10 (C-3) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 1-45 situés au niveau N-terminus de Septin 10 d'origine human
- recommandé pour la détection de Septin 10 isoforms 1 and 2 d'origine human par WB, IP, IF, IHC(P) et ELISA
- 2a BP-HRP">m-IgG2a BP-HRP est le réactif de détection secondaire préféré pour l'anticorps Septin 10 (C-3) pour les applications WB et IHC(P). Ce réactif est désormais proposé en association avec l'anticorps Septin 10 (C-3)(voir les informations relatives à la commande ci-dessous).
The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. Septin 10, a 517- residue polypeptide which localizes to the cytoplasm and nucleus, shares closest homology to Septin 6 and Septin 8. Septin 10 is expressed ubiquitously, though most abundantly in the placenta, lung, kidney, heart, skeletal muscles, liver and various tumor cell lines. Like other septin family members, Septin 10 displays GTP-binding and GTPase activity. Additionally, Septin 10 is potentially involved in cytokinesis. Upon maturation induced by lipopolysaccharide (LPS), dendritic cells express upregulated amounts of Septin 10.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Septin 10 (C-3) | sc-365776 | 200 µg/ml | $316.00 | |||
Septin 10 (C-3): m-IgG2a BP-HRP Kit | sc-546047 | 200 µg Ab; 10 µg BP | $354.00 |