Se46.8 Antibody (C-12): sc-377273

Se46.8 Antibody (C-12) is a mouse monoclonal IgG2b antibody that detects Se46.8 protein of Streptococcus equi origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Se46.8 is an 86 amino acid surface protein that plays a crucial role in the interaction between the pathogen and the host, potentially serving as a biomarker for serodiagnosis and as a component in subunit vaccines. Surface proteins like Se46.8 are vital for the pathogenicity of Streptococcus equi subspecies equi, which is a clonal, equine host-adapted pathogen responsible for the highly contagious disease known as strangles. This disease is characterized by severe tonsillitis and lymphadenitis, leading to symptoms such as fever, depression, and significant swelling of the lymph nodes in the head and neck, which can result in respiratory distress. The infection is primarily transmitted through inhalation of S. equi or direct contact with the mucopurulent discharge from infected animals. Understanding Se46.8 function is essential, as Se46.8 may provide insights into the mechanisms of infection and aid in the development of effective diagnostic and therapeutic strategies against strangles.

The preferred Se46.8 antibody is Se46.8 Antibody (C-10): sc-377238.