ACCÈS RAPIDE AUX LIENS
Secretory carrier membrane proteins (SCAMPs) are components of the post Golgi membranes and are invovled in endocytosis, vesicle recycling and membrane trafficking. The structural features of SCAMPs include multiple N-terminal NPF repeats and four highly conserved transmembrane regions. These NPF repeats frequently interact with EH domain proteins and aid in the budding of transport vesicles from the plasma membrane or the Golgi complex. Endocytic budding at the plasma membrane and vesicle budding at the trans-Golgi complex facilitates binding of SCAMP proteins to EH domain proteins. SCAMPs exist as distinct but related proteins that include SCAMP1, SCAMP2, and SCAMP3. Tyrosine-phosphorylation by the epidermal growth factor-receptor of SCAMP1 and SCAMP3 suggests that SCAMPs are regulated by phosphorylation. Although SCAMPs are ubiquitously expressed throughout all tissue, in neural tissue the synaptic vesicles express a particularly high concentration of SCAMP1.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SCAMP1 (G-8) | sc-393236 | 200 µg/ml | $316.00 | |||
SCAMP1 (G-8): m-IgG Fc BP-HRP Kit | sc-538173 | 200 µg Ab; 10 µg BP | $354.00 | |||
SCAMP1 (G-8): m-IgGκ BP-HRP Kit | sc-535733 | 200 µg Ab; 40 µg BP | $354.00 | |||
SCAMP1 (G-8): m-IgG1 BP-HRP Kit | sc-545559 | 200 µg Ab; 20 µg BP | $354.00 |