Anticorps SART-1 (E-2): sc-376307
- L'Anticorps SART-1 (E-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 107-406 situés près de la région N-terminus de SART-1 d'origine human
- recommandé pour la détection de SART-1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour SART-1 Antibody (E-2) for WB applications. Ces réactifs sont désormais proposés en lots avec SART-1 Antibody (E-2)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
SART-1 (squamous cell carcinoma antigen recognized by T cells), also known as Ara1, HOMS1 or Snu66, is a ubiquitously expressed protein that is involved in mRNA splicing and cell proliferation. The gene encoding SART-1 is posttranscriptionally modified to produce two proteins: SART-1(800), which is the native transcript and is localized to the nucleus of proliferating cells, and SART-1(259), which is expressed in the cytosol of epithelial cancers. While both proteins are involved in regulating cell proliferation, SART-1(259) is also an essential component in the spliceosome C assembly pathway playing a role in pre-mRNA splicing. SART-1(259) possesses a tumor-rejection antigen that can induce restricted cytotoxic T lymphocytes in cancer patients, suggesting a possible role in immunotherapy. Additionally, the polymorphic variation within the SART-1 gene may be a cause of atopy, an allergic hypersensitivity characterized by eczema, asthma and allergic conjunctivitis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SART-1 (E-2) | sc-376307 | 200 µg/ml | $316.00 | |||
SART-1 (E-2): m-IgG Fc BP-HRP Kit | sc-540543 | 200 µg Ab; 10 µg BP | $354.00 | |||
SART-1 (E-2): m-IgG1 BP-HRP Kit | sc-542194 | 200 µg Ab; 20 µg BP | $354.00 |