The Reticulon (Rtn) family consists of four members: Rtn-1 (also designated neuroendocrine-specific protein or NSP), Rtn-2 (also designated NSP-like-1), Rtn-3 (also designated NSP-like-2) and Nogo (also designated Rtn-4A). Reticulon proteins are anchored to the membranes of the endoplasmic reticulum through their common C-terminal regions. Localized on human chromosome 14q23.1, the gene encoding Rtn-1 is expressed as three isoforms: Rtn-1A (NSP-A), Rtn-1B (NSP-B) and Rtn-1C (NSP-C). The gene encoding human Rtn-2 is located on chromosome 19q13 and also encodes three isoforms. Rtn-2-A and Rtn-2-C are produced by the use of alternative initiation sites, whereas Rtn-2-B is an alternative splice variant of the Rtn-2-A isoform. Rtn-2-A and Rtn-2-B are highly expressed in brain, while Rtn-2-C is primarily expressed in skeletal muscle.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Rtn-2 (PL-A9) | sc-134431 | 100 µg/ml | $333.00 |