Anticorps RNMTL1 (A-5): sc-398973
- L'Anticorps RNMTL1 (A-5) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 269-287 au niveau d'une région interne de RNMTL1 d'origine human
- recommandé pour la détection de RNMTL1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps RNMTL1 (A-5) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps RNMTL1 (A-5)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The RNA methyltransferase family of proteins catalyze the transfer of a methyl group from a donor to an RNA acceptor. Via their ability to modify RNA, RNA methyltransferase proteins play an important role in cell growth and signaling pathways and may be involved in tumor development and progression. RNMTL1 (RNA methyltransferase like 1), also known as HC90, is a 420 amino acid protein belonging to the RNA methyltransferase trmH family. Expressed in normal liver and hepatocarcinoma, RNMTL1 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RNMTL1 (A-5) | sc-398973 | 200 µg/ml | $316.00 | |||
RNMTL1 (A-5): m-IgG Fc BP-HRP Kit | sc-538554 | 200 µg Ab; 10 µg BP | $354.00 | |||
RNMTL1 (A-5): m-IgGκ BP-HRP Kit | sc-536191 | 200 µg Ab; 40 µg BP | $354.00 | |||
RNMTL1 (A-5): m-IgG1 BP-HRP Kit | sc-545763 | 200 µg Ab; 20 µg BP | $354.00 | |||
RNMTL1 (A-5) peptide neutralisant | sc-398973 P | 100 µg/0.5 ml | $68.00 |