Rheb Antibody (80-R): sc-130398

Rheb Antibody (80-R) is a mouse monoclonal IgG1 kappa light chain antibody that detects Rheb in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP). Anti-Rheb antibody (80-R) is available in a non-conjugated form, allowing for versatile applications in research. Rheb, or Ras homolog enriched in brain, plays a crucial role in cellular signaling pathways, particularly in the regulation of mTOR (mechanistic target of rapamycin) signaling, which is vital for cell growth, proliferation, and survival. Rheb is primarily located in the cytoplasm and can translocate to the lysosome, where Rheb interacts with mTORC1 (mTOR complex 1) to promote anabolic processes. This localization is significant because Rheb integrates signals from growth factors and nutrient availability, thereby influencing cellular metabolism and growth. Dysregulation of Rheb and associated signaling pathways has been implicated in various cancers and metabolic disorders, making Rheb an important target for therapeutic intervention. Rheb monoclonal antibody (80-R) is an essential tool for researchers studying these critical pathways and their implications in health and disease.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Rheb Antibody (80-R) has 6 citations in a variety of scientific publications.

Primary antibodies like Anti-Rheb Antibody (80-R) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Rheb Antibody (80-R) Specifications

Alternate Product Name: Rheb

Product Clone Name: 80-R

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-185

Epitope Target: Rheb

Epitope Species: human

Product Reactivity/Detection: Rheb

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 6 citations in various scientific publications

Available Conjugates/Forms for Rheb Antibody (80-R): N/A

The preferred Rheb antibody is Rheb Antibody (B-12): sc-271509.