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Structurally, C-C or b-chemokines are characterized by a set of conserved, adjacent cysteines. Members of this family include MCP-1, MCP-2, MCP-3, MIP-1α, MIP-1β, RANTES and I-309. RANTES (regulated upon activation, normal T cell expressed and secreted) is expressed by platelets, eosinophils, fibroblasts, macrophages, endothelial cells and T lymphocytes. Consistent with its belonging to the chemokine family, RANTES exhibits strong chemoattractant activity towards monocytes and NK cells. I-309 was initially identified as a factor present in g/d T lymphocytes. I-309 cDNA encodes a protein 73 amino acids in length with one potential N-linked glycosylation site. Unlike the other members of the C-C family, I-309 does not induce chemotaxis in natural killer (NK) cells.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
LI-COR® et Odyssey® sont marques déposées de LI-COR Biosciences
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RANTES (C-12) | sc-373984 | 200 µg/ml | $316.00 | |||
RANTES (C-12): m-IgG3 BP-HRP Kit | sc-550444 | 200 µg Ab; 40 µg BP | $354.00 | |||
RANTES (C-12) peptide neutralisant | sc-373984 P | 100 µg/0.5 ml | $68.00 |