Date published: 2025-9-9

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Anticorps rabphilin-3A (E-3): sc-398621

5.0(1)
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Fiches techniques
  • L'Anticorps rabphilin-3A (E-3) est un monoclonal de souris mouse IgM κ (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 499-533 au niveau d'une région interne de rabphilin-3A d'origine mouse
  • recommandé pour la détection de rabphilin-3A d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire rabphilin-3A (E-3). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The carboxy-terminal of rabphilin-3A consists of two C2 domains, A and B, and the amino-terminal (residues 45-170) contains a cysteine-rich rich region with two zinc finger motifs. Rabphilin-3A belongs to a family of other carboxy-terminal type (C-type) tandem C2 proteins, which includes synaptotagmins and Doc2. Rabphilin is expressed in neuroendocrine cells and co-localizes with Rab3A on synaptic vesicles and chromaffin granules. Rabphilin-3A binds Rab3a/GTP/Mg+ within amino-terminal residues 45 and 170. Rabphilin-3A binds calcium ions and phosphatidylinositol 4,5-bisphophate containing lipid vesicles within its C2 domains. Rabphilin-3A is a positive regulator of calcium dependent exocytosis, while Rab3a is a negative regulator of exocytosis. Although rabphilin-3A associates with Rab3a, they seem to influence exocytosis independently of each other. Rabphilin-3A effects are likely mediated through interactions with an unknown factor that recognizes the Rab3 binding domain.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps rabphilin-3A (E-3)

    sc-398621
    200 µg/ml
    $316.00

    rabphilin-3A (E-3) peptide neutralisant

    sc-398621 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-398621 P appropriate for?

    Posée par: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-27
    • y_2025, m_9, d_8, h_8CST
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    Rated 5 de 5 de par Satisfactory Western blot data of rabphilinSatisfactory Western blot data of rabphilin-3A expression in non-transfected and mouse rabphilin-3A transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-10-09
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    Anticorps rabphilin-3A (E-3) est évalué 5.0 de 5 de 1.
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