Date published: 2025-9-8

00800 4573 8000

SCBT Portrait Logo
Seach Input

Anticorps rabphilin-3A (E-2): sc-390915

5.0(1)
Écrire une critiquePoser une question

Fiches techniques
  • L'Anticorps rabphilin-3A (E-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 516-576 dans une région interne de rabphilin-3A d'origine human
  • recommandé pour la détection de rabphilin-3A d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps rabphilin-3A (E-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps rabphilin-3A (E-2)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The carboxy-terminal of rabphilin-3A consists of two C2 domains, A and B, and the amino-terminal (residues 45-170) contains a cysteine-rich rich region with two zinc finger motifs. Rabphilin-3A belongs to a family of other carboxy-terminal type (C-type) tandem C2 proteins, which includes synaptotagmins and Doc2. Rabphilin is expressed in neuroendocrine cells and co-localizes with Rab3A on synaptic vesicles and chromaffin granules. Rabphilin-3A binds Rab3a/GTP/Mg+ within amino-terminal residues 45 and 170. Rabphilin-3A binds calcium ions and phosphatidylinositol 4,5-bisphophate containing lipid vesicles within its C2 domains. Rabphilin-3A is a positive regulator of calcium dependent exocytosis, while Rab3a is a negative regulator of exocytosis. Although rabphilin-3A associates with Rab3a, they seem to influence exocytosis independently of each other. Rabphilin-3A effects are likely mediated through interactions with an unknown factor that recognizes the Rab3 binding domain.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps rabphilin-3A (E-2)

    sc-390915
    200 µg/ml
    $316.00

    rabphilin-3A (E-2): m-IgG Fc BP-HRP Kit

    sc-538113
    200 µg Ab; 10 µg BP
    $354.00

    rabphilin-3A (E-2): m-IgGκ BP-HRP Kit

    sc-535664
    200 µg Ab; 40 µg BP
    $354.00

    rabphilin-3A (E-2): m-IgG1 BP-HRP Kit

    sc-545529
    200 µg Ab; 20 µg BP
    $354.00

    Are there any issues with using sc-390915: rabphilin-3A (E-2) mouse monoclonal primary antibody on mouse samples?

    Posée par: Professor Griffin
    Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-390915 conjugates.
    Répondue par: Technical Support
    Date de publication: 2017-03-07
    • y_2025, m_8, d_29, h_8CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_fr_FR, sid_390915, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 126ms
    • QUESTIONS, PRODUCT
    Rated 5 de 5 de par Satisfactory Western blot data of rabphilinSatisfactory Western blot data of rabphilin-3A expression in rat brain and human hippocampus tissue extracts. -SCBT QC
    Date de publication: 2014-06-21
    • y_2025, m_8, d_29, h_8
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_fr_FR, sid_390915, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 19ms
    • REVIEWS, PRODUCT
    Anticorps rabphilin-3A (E-2) est évalué 5.0 de 5 de 1.
    • y_2025, m_8, d_29, h_8
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_fr_FR, sid_390915, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 122ms
    • REVIEWS, PRODUCT