Date published: 2025-9-8

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Anticorps Rabex-5 (D-8): sc-166050

5.0(1)
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Fiches techniques
  • L'Anticorps Rabex-5 (D-8) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • soulevée contre les acides aminés 421-708 correspondant à C-terminus de Rabex-5 d'origine human.
  • recommandé pour la détection de Rabex-5 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour Rabex-5 Antibody (D-8) pour les applications WB. Ces réactifs sont désormais proposés en lots avec Rabex-5 Antibody (D-8)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Rabex-5 (Rab 5 GDP/GTP exchange factor), also known as RABGEF1, RAP1 or RABAPTIN-5-associated exchange factor for Rab 5, is a Rab guanine nucleotide exchange factor. Rabex-5 localizes to the cytoplasm and can associate with early endosomes. It consists of an N-terminal zinc finger domain, a GEF domain, an EET (early endosomal targeting) domain and a coiled-coil domain. The EET domain is important for the association of Rabex-5 with early endosomes and for the activation of Rab 5. Truncated Rabex-5 that is missing its EET domain can still function via an association with RABAPTIN-5. The Rabex-5/RABAPTIN-5 complex can target to early endosomes in a Rab 5-dependent manner through the binding of Rab5-GTP to RABAPTIN-5. In vitro, Rabex-5 exhibits GEF activity on its own, however, its association with RABAPTIN-5 increases its efficiency.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps Rabex-5 (D-8)

    sc-166050
    200 µg/ml
    $316.00

    Rabex-5 (D-8): m-IgG Fc BP-HRP Kit

    sc-539998
    200 µg Ab; 10 µg BP
    $354.00

    Rabex-5 (D-8): m-IgG2a BP-HRP Kit

    sc-546833
    200 µg Ab; 10 µg BP
    $354.00

    How much sample do you recommend loading on the gel for Western blot detection using Rabex-5 (D-8): sc-166050?

    Posée par: Professor Griffin
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_8, h_8CST
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    Rated 5 de 5 de par Satisfactory Western blot data of RabexSatisfactory Western blot data of Rabex-5 expression in non-transfected and human Rabex-5 transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-03-29
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    Anticorps Rabex-5 (D-8) est évalué 5.0 de 5 de 1.
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