QTRTD1 (queuine tRNA-ribosyltransferase domain containing 1) is a 415 amino acid protein involved in tRNA modification and tRNA-queuosine biosynthesis. Localizing to cytoplasm, QTRTD1 also localizes to the mitochondrial outer membrane and associates with QTRT1 (queuine tRNA-ribosyltransferase domain containing 1) to form an active queuine tRNA-ribosyltransferase. At the wobble position of tRNAs with GUN anticodons, QTRTD1 exchanges queuine for guanine to form queuosine, a modified nucleoside. QTRTD1 is a member of the queuine tRNA-ribosyltransferase family, QTRTD1 subfamily and is encoded by a gene located on human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps QTRTD1 (B-11) | sc-377384 | 200 µg/ml | $316.00 | |||
QTRTD1 (B-11) peptide neutralisant | sc-377384 P | 100 µg/0.5 ml | $68.00 |