Anticorps PRPK (G-10): sc-398705
- L'Anticorps PRPK (G-10) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 190-253 situés au niveau C-terminus de PRPK d'origine human
- recommandé pour la détection de PRPK d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps PRPK (G-10) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps PRPK (G-10)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation and cell cycle control mechanisms. PRPK (p53-related protein kinase), also known as TP53RK, is a 253 amino acid protein kinase that phosphorylates Ser15 of p53. PRPK phosphorylation of p53 causes increased stabilization and activity of p53. CGI-121 may act as an inhibitor of the PRPK-p53 interaction, thus preventing the phosphorylation of p53. Unphosphorylated p53 is degraded by the ubiquitin-proteasome pathway, which may ultimately lead to cell proliferation. PRPK contains a protein kinase domain with a conserved catalytic core. PRPK is localized to the nucleus of the cell and is highly expressed in testis, with lower expression in heart, kidney and spleen.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PRPK (G-10) | sc-398705 | 200 µg/ml | $316.00 | |||
PRPK (G-10): m-IgG Fc BP-HRP Kit | sc-538507 | 200 µg Ab; 10 µg BP | $354.00 | |||
PRPK (G-10): m-IgGκ BP-HRP Kit | sc-536133 | 200 µg Ab; 40 µg BP | $354.00 | |||
PRPK (G-10): m-IgG1 BP-HRP Kit | sc-545737 | 200 µg Ab; 20 µg BP | $354.00 |