Anticorps Procainamide (708): sc-66077

Procainamide is a class Ia drug used for the clinical treatment of cardiac arrhythmias. It functions by blocking open sodium channels, thereby prolonging the cardiac action potential. This leads to a slowed conduction, and ultimately a decreased rate of rise of the action potential, which may result in widening of QRS on electrocardiogram. The active metabolite in this drug is N-acetyl procainamide, which is excreted by the kidneys and the renal system. Procainamide may be administered intravenously or orally and can be used for both supraventricular and ventricular arrhythmias. Problematic side effects of Procainamide include rash, myalgia, and hypersensitivity reactions. In some cases, Procainamide may cause an antibody production against cellular components, which can lead to systemic lupus erythematosus-like reactions.