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PPIH (peptidylprolyl isomerase H (cyclophilin H)), also known as PPIase H, Rotamase H, CypH, CYP20 or USA-CYP (U-snRNP-associated cyclophilin SnuCyp-20), is a 177 amino acid protein that belongs to the cyclophilin-type PPIase family. PPIH may accelerate the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIH is thought to participate in pre-mRNA splicing with processing factors PRPF3, PRPF4, and PRPF18 and may be involved in the assembly of the U4/U5/U6 tri-snRNP complex. Considered a protein chaperone, PPIH possesses PPlase activity and mediates the interactions between different proteins inside the spliceosome. PPIH contains one PPIase cyclophilin-type domain and is inhibited by cyclosporin A.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PPIH (G-6) | sc-377420 | 200 µg/ml | $316.00 | |||
PPIH (G-6) peptide neutralisant | sc-377420 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps PPIH (G-6) X | sc-377420 X | 200 µg/0.1 ml | $316.00 |