Date published: 2025-9-9

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Anticorps PP1β (D-11): sc-377125

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Fiches techniques
  • L'Anticorps PP1β (D-11) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 2-31 au niveau N-terminus de PP1β d'origine human
  • recommandé pour la détection de PP1β d'origine mouse, rat, human et avian par WB, IP, IF, IHC(P) et ELISA; également réactif avec d'autres espèces, dont et canine, bovine, porcine and avian
  • Voir PP1 (E-9): sc-7482 pour d'autres anticorps conjugués PP1β, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps PP1β (D-11) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps PP1β (D-11) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP1 family is comprised of subfamily members PP1α, PP1β and PP1γ, which are MgATP-dependent enzymes. PP1 inactivity is maintained through its association with the inhibitory protein NIPP-1 (nuclear inhibitor of PP1). Phosphorylation of NIPP-1 by cAMP-PK or casein kinase II results in the release of active PP1.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PP1β (D-11)

    sc-377125
    200 µg/ml
    $316.00

    PP1β (D-11): m-IgG Fc BP-HRP Kit

    sc-540695
    200 µg Ab; 10 µg BP
    $354.00

    PP1β (D-11): m-IgG1 BP-HRP Kit

    sc-542304
    200 µg Ab; 20 µg BP
    $354.00

    PP1β (D-11) peptide neutralisant

    sc-377125 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-377125 P appropriate for?

    Posée par: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-27
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    Rated 5 de 5 de par Superb immunoperoxidase nuclear and cytoplasmicSuperb immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human cerebellum tissue. -SCBT QC
    Date de publication: 2015-01-30
    Rated 5 de 5 de par Produced positive Western Blot data of PP1Produced positive Western Blot data of PP1 expression in HeLa and SJRH30 whole cell lysates. -SCBT QC
    Date de publication: 2014-09-06
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    Anticorps PP1β (D-11) est évalué 5.0 de 5 de 2.
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