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POGK (pogo transposable element with KRAB domain), also known as BASS2 or LST003, is a 609 amino acid protein that may be a member of the DNA-mediated transposon family. Localizing to the nucleus, POGK contains an N-terminal KRAB (Kruppel-associated box) domain, an HTH CENP-B-type (helix-turn-helix and centromere protein B-type) DNA-binding domain and a C-terminal DDE domain. The KRAB domain is a potent transcriptional repression motif and is approximately 75 amino acids in length. DDE domains are catalytic motifs consisting of two conserved aspartic acids separated by 70 amino acids and a conserved glutamic acid that is further separated by another 35 amino acids. DDE domains are characteristic of DNA transposases and retroviral integrases.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps POGK (5Q13) | sc-100648 | 100 µg/ml | $333.00 |