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Purine nucleoside phosphorylase (PNP), also designated inosine phosphorylase, forms a homotrimer. It belongs to the PNP/MTAP phosphorylase family of proteins. Human PNP catalyzes the reversible phosphorolysis of ribonucleosides and 2′-deoxyribonucleosides with specificity for guanine, hypoxanthine, and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Children with PNP deficiency are highly prone to infections, autoimmune disorders, neurological impairment, and cancer.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PNP (H-7) | sc-365081 | 200 µg/ml | $316.00 | |||
PNP (H-7): m-IgGκ BP-HRP Kit | sc-535148 | 200 µg Ab; 40 µg BP | $354.00 | |||
PNP (H-7): m-IgG2b BP-HRP Kit | sc-549345 | 200 µg Ab; 10 µg BP | $354.00 |