Date published: 2025-9-8

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Anticorps PINX1 (A-9): sc-376588

5.0(1)
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Fiches techniques
  • L'anticorps PINX1 A-9 est un monoclonal IgG1 de souris fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 8-29 au niveau N-terminus de PINX1 d'origine human
  • recommandé pour la détection de PINX1 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour PINX1 Antibody (A-9) for WB applications. Ces réactifs sont désormais proposés en lots avec PINX1 Antibody (A-9)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    PINX1 (PIN2/TRF1-interacting protein X1), also known as LPTL or LPTS (liver-related putative tumor suppressor), is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. PINX1 contains one G-patch domain and one telomeric inhibiting domain (TID) at its C-terminus. PINX1 interacts with the telomere protein TRF1 and the telomerase reverse transcriptase TERT. The TID domain of PINX1 specifically interacts with TERT and functions to inhibit its activity, thus participating in the regulation of telomerase activity. Overexpression of PINX1 leads to shortened telomeres, further supporting an inhibitory role of PINX1 on telomerase activity. The depletion of PINX1 significantly increases telomerase activity and may lead to tumorigenicity of cancer cells. This suggests that PINX1 acts as a tumor suppressor and can inhibit cell proliferation. In addition, PINX1 is involved in nucleolar RNA maturation.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PINX1 (A-9)

    sc-376588
    200 µg/ml
    $316.00

    PINX1 (A-9): m-IgG Fc BP-HRP Kit

    sc-540603
    200 µg Ab; 10 µg BP
    $354.00

    PINX1 (A-9): m-IgG1 BP-HRP Kit

    sc-542237
    200 µg Ab; 20 µg BP
    $354.00

    PINX1 (A-9) peptide neutralisant

    sc-376588 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-376588 P appropriate for?

    Posée par: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_1, h_4CST
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    Rated 5 de 5 de par Produced positive Western blot data of PINX1Produced positive Western blot data of PINX1 expression in non-transfected and human PINX1 transfected 293 whole cell lysates. -SCBT QC
    Date de publication: 2013-01-10
    • y_2025, m_9, d_1, h_4
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    Anticorps PINX1 (A-9) est évalué 5.0 de 5 de 1.
    • y_2025, m_9, d_1, h_4
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