Anticorps PIBF (C-9): sc-166372
- L'Anticorps PIBF (C-9) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 428-458 au niveau d'une région interne de PIBF d'origine human
- recommandé pour la détection de PIBF d'origine mouse, rat et human par WB, IP, IF et ELISA
- 1 BP-HRP">m-IgG1 BP-HRP est le réactif de détection secondaire préféré pour l'anticorps PIBF (C-9) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps PIBF (C-9)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
PIBF (Progesterone-Induced Blocking Factor 1) is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells). In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF is associated with the nucleus, whereas secretion of shorter forms is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines. The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PIBF (C-9) | sc-166372 | 200 µg/ml | $316.00 | |||
PIBF (C-9): m-IgG1 BP-HRP Kit | sc-542662 | 200 µg Ab; 20 µg BP | $354.00 | |||
PIBF (C-9) peptide neutralisant | sc-166372 P | 100 µg/0.5 ml | $68.00 |