Date published: 2025-9-8

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Anticorps PGRP-L (A-5): sc-166825

5.0(2)
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Fiches techniques
  • L'Anticorps PGRP-L (A-5) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 23-322 situés près de la région N-terminus de PGRP-L d'origine mouse
  • recommandé pour la détection de PGRP-L d'origine mouse par WB, IP, IF, IHC(P) et ELISA
  • m-IgG2a BP-HRP est le réactif secondaire recommandé pour la détection de l'anticorps PGRP-L (A-5) pour des applications de WB and IHC(P). Ce réactif est maintenant proposé en kit avec l'anticorps PGRP-L (A-5) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Peptidoglycan recognition protein-L (PGRP-L) is a pattern recognition molecule consisting of 576 amino acid residues. It is the longest and most widely expressed member of the PGRP family. PGRP-L is a Zn2+-dependent protein with N-acetylmuramyl-L-alanine-amidase activity that digests peptidoglycan. PGRP-L can form a homodimer and may dimerize with other PGRP proteins. It is a secreted serum protein but is also expressed as a transmembrane protein in liver parenchymal cells binding peptidoglycan and Gram-positive bacteria. PGRP-L deficient mice exhibit slightly lower levels of IL-6 and TNFα but exhibit no obvious phenotypic abnormalities. This suggests that PGRP-L may play a minor role in innate immune functions. In addition, PGRP-L may be a key player in the activation of Nod1, an intracellular pattern recognition protein.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PGRP-L (A-5)

    sc-166825
    200 µg/ml
    $316.00

    PGRP-L (A-5): m-IgG2a BP-HRP Kit

    sc-546033
    200 µg Ab; 10 µg BP
    $354.00

    Can PGRP-L (A-5): sc-166825 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Trav11
    Thank you for your question. Yes, PGRP-L (A-5): sc-166825 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_8, d_28, h_5CST
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    Rated 5 de 5 de par Great immunoperoxidase cytoplasmic stainingGreat immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human liver tissue. -SCBT QC
    Date de publication: 2015-05-18
    Rated 5 de 5 de par Good Western Blot data of PGRPGood Western Blot data of PGRP-L expression in non-transfected and mouse PGRP-L transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-05-13
    • y_2025, m_8, d_28, h_5
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    Anticorps PGRP-L (A-5) est évalué 5.0 de 5 de 2.
    • y_2025, m_8, d_28, h_5
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