Poly(ADP-ribose) polymerase-3 (PARP-3) is part of the base excision repair (BER) pathway, catalyzing the poly(ADP-ribosyl)ation of nuclear proteins. Poly(ADP-ribosyl)ation, a post-translational modification following DNA damage, appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-3 is a nuclear, DNA-binding protein, which interacts with PARP-1. PARP-3 is present in actively dividing tissues with highest levels in the kidney, skeletal muscle, liver, heart and spleen. Human PARP-3 maps to chromosome 3p21-3-p21.1, a gene region that undergoes alteration in solid malignant tumors.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PARP-3 (C-1) | sc-390758 | 200 µg/ml | $316.00 | |||
PARP-3 (C-1): m-IgG Fc BP-HRP Kit | sc-540849 | 200 µg Ab; 10 µg BP | $354.00 | |||
PARP-3 (C-1): m-IgG1 BP-HRP Kit | sc-542414 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps PARP-3 (C-1) X | sc-390758 X | 200 µg/0.1 ml | $316.00 |