Anticorps PAFAH1B3 (37-K): sc-81950
- L'Anticorps PAFAH1B3 (37-K) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 100 µg/ml
- dirigé contre la PAFAH1B3 recombinante d'origine human
- recommandé pour la détection de PAFAH1B3 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire PAFAH1B3 (37-K). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The platelet activating factor (PAF) acetylhydrolases catalyze hydrolysis of the sn-2 ester bond of PAF and related pro-inflammatory phospholipids and thus attenuate their bioactivity. The family of PAF acetylhydrolases includes one secreted plasma isozyme and two intracellular isozymes. The intracellular isozymes are distinguished by differences in their primary sequence, tissue localization, subunit composition and substrate preferences. The most thoroughly characterized intracellular isoform, PAFAH1B, is a heterotrimeric protein expressed in brain tissue and plays and important role in brain development and function. PAFAH1B is comprised of a regulatory subunit (LIS1) and two homologous (63% identity) catalytic subunits (PAFAH1B2 and PAFAH1B3), which harbor all the activity of the enzyme. The PAFAH1B2 and PAFAH1B3 subunits readily associate with very high affinity to form heterodimers, and this dimerization is essential for both stability and catalytic activity. PAFAH1B3 is also commonly known as PAFAH1B 29kDa subunit, PAFAH1B subunit γ or PAFAH1B subunit α1.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PAFAH1B3 (37-K) | sc-81950 | 100 µg/ml | $333.00 |