Protein kinases catalyze the phosphorylation of serine, threonine or tyrosine residues in target substrates, providing a mechanism of control for myriad cellular signaling pathways. Several families of kinases phosphorylate both serine and threonine residues in target substrates, including the Raf, Rsk, ROCK, PAK, Ak, and PKC families of serine/threonine protein kinases. The modification of proteins by phosphorylation can result in three dimensional changes to the structure of the protein and thereby alter its enzymatic activity or its ability to interact with other proteins. Antibodies targeted to phosphoserine may be used for the characterization of proteins with phosphorylated serine residues, and for the elucidation of cellular pathways involving serine phosphorylation.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps p-Ser/Phosphoserine (4A9) | sc-81517 | 50 µg/0.5 ml | $316.00 |