Anticorps OSM (E-4): sc-365136
- L'Anticorps OSM (E-4) est un monoclonal de souris IgG3 κ, cité dans 1 publications, fourni en 200 µg/ml
- spécifique pour une correspondance épitopique entre les acides aminés 3-25 au sein de N-terminus de OSM d'origine human.
- recommandé pour la détection de OSM d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG3 BP-HRP est le réactif de détection secondaire préféré pour OSM Anticorps (E-4) pour les applications WB. Ce réactif est désormais proposé dans un ensemble avec OSM Anticorps (E-4)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Oncostatin M (OSM) is a glycoprotein that was originally isolated from the conditioned medium of U937 human histiocytic leukemia cells that had been induced to differentiate into macrophage-like cells by treatment with phorbol 12-myristate 13 acetate. OSM inhibits the growth of a broad range of human tumor cell lines, but does not influence the growth of normal human fibroblasts. High-affinity binding sites for OSM have been detected on normal and tumor cells, and a receptor has been identified by chemical cross-linking studies. Expression of OSM is greatest in activated monocytic and lymphocytic cell lines and in normal adherent macrophages. Amino acid sequence analysis of OSM has revealed homology with leukemia inhibitory factor (LIF), granulocyte colony stimulating factor (G-CSF) and interleukin 6 (IL-6), all of which affect the growth and differentiation of a broad range of cell types, including those of hematopoietic origin.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps OSM (E-4) | sc-365136 | 200 µg/ml | $316.00 | |||
OSM (E-4): m-IgG3 BP-HRP Kit | sc-550419 | 200 µg Ab; 40 µg BP | $354.00 | |||
OSM (E-4) peptide neutralisant | sc-365136 P | 100 µg/0.5 ml | $68.00 |