Date published: 2025-9-7

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Anticorps OSBP2 (G-8): sc-365951

5.0(2)
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Fiches techniques
  • L'anticorps OSBP2 G-8 est un monoclonal IgM de souris fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 479-507 au niveau d'une région interne de OSBP2 d'origine mouse
  • recommandé pour la détection de OSBP2 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire OSBP2 (G-8). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps OSBP2 (G-8)

    sc-365951
    200 µg/ml
    $316.00

    OSBP2 (G-8) peptide neutralisant

    sc-365951 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365951 P appropriate for?

    Posée par: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-28
    • y_2025, m_8, d_30, h_9CST
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    Rated 5 de 5 de par Beautiful immunofluorescence membrane stainingBeautiful immunofluorescence membrane staining in methanol-fixed NIH/3T3 cells. -SCBT QC
    Date de publication: 2015-01-10
    Rated 5 de 5 de par Produced positive Western Blot data of OSBP2Produced positive Western Blot data of OSBP2 expression in F9 whole cell lysate. -SCBT QC
    Date de publication: 2013-11-11
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    Anticorps OSBP2 (G-8) est évalué 5.0 de 5 de 2.
    • y_2025, m_8, d_30, h_9
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