ACCÈS RAPIDE AUX LIENS
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis as well as in viral infection resistance. OAS2, which represents the "medium form" in the OAS family, contains two OAS1-homologous domains separated by a proline-rich putative linker region. It is functionally active as a dimer. Abnormal expression patterns of OAS2 may be linked to infection flare in Lupus patients.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps OAS2 (C-1) | sc-374238 | 200 µg/ml | $316.00 | |||
OAS2 (C-1): m-IgG Fc BP-HRP Kit | sc-540428 | 200 µg Ab; 10 µg BP | $354.00 | |||
OAS2 (C-1): m-IgG1 BP-HRP Kit | sc-542115 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps OAS2 (C-1) X | sc-374238 X | 200 µg/0.1 ml | $316.00 |