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NURIM, also known as NRM or NRM29, is a 262 amino acid multi-pass membrane protein that localizes to the inner membrane of the nucleus. Existing as multiple alternatively spliced isoforms, NURIM is thought to possess enzymatic functions that may play a role in nuclear envelope (NE) dynamics. The gene encoding NURIM maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NURIM (B-1) | sc-390174 | 200 µg/ml | $316.00 | |||
NURIM (B-1): m-IgG Fc BP-HRP Kit | sc-540766 | 200 µg Ab; 10 µg BP | $354.00 | |||
NURIM (B-1): m-IgG1 BP-HRP Kit | sc-542358 | 200 µg Ab; 20 µg BP | $354.00 | |||
NURIM (B-1) peptide neutralisant | sc-390174 P | 100 µg/0.5 ml | $68.00 |