Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup50 (nucleoporin 50), also known as NPAP60 or NPAP60L (nuclear pore-associated protein 60 kDa-like), is a 468 amino acid nuclear protein that functions as a binding site for export receptor-cargo complexes. Localizing to the nucleoplasmic fibrils of the nuclear pore complex, Nup50 associates with various transport receptor proteins including p27. While ubiquitously expressed, Nup50 is found at highest levels in peripheral blood leukocytes, testis and fetal liver, and contains multiple FG repeats in addition to a single RanBD1 domain.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Nup50 (B-6) | sc-398992 | 200 µg/ml | $316.00 | |||
Nup50 (B-6): m-IgG Fc BP-HRP Kit | sc-538564 | 200 µg Ab; 10 µg BP | $354.00 | |||
Nup50 (B-6): m-IgGκ BP-HRP Kit | sc-536202 | 200 µg Ab; 40 µg BP | $354.00 | |||
Nup50 (B-6): m-IgG2a BP-HRP Kit | sc-548341 | 200 µg Ab; 10 µg BP | $354.00 |