Anticorps NumbL (H-5): sc-390799
- L'Anticorps NumbL (H-5) est un monoclonal de souris mouse IgG2a κ (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 331-410 dans une région interne de NumbL d'origine human
- recommandé pour la détection de NumbL d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 2a BP-HRP">m-IgG2a BP-HRP sont les réactifs de détection secondaire préférés pour NumbL Antibody (H-5) pour les applications WB. Ces réactifs sont désormais proposés en lots avec NumbL Antibody (H-5)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
In Drosophila, neuronal cell fate decisions are directed by NUMB, a signaling adapter protein with two protein-protein interaction domains, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NumbL (H-5) | sc-390799 | 200 µg/ml | $316.00 | |||
NumbL (H-5): m-IgG Fc BP-HRP Kit | sc-540855 | 200 µg Ab; 10 µg BP | $354.00 | |||
NumbL (H-5): m-IgG2a BP-HRP Kit | sc-546966 | 200 µg Ab; 10 µg BP | $354.00 |