NOTCH2NL Antibody (39-Y): sc-100307
- NOTCH2NL Antibody (39-Y) is a mouse monoclonal IgG1 κ NOTCH2NL antibody, cited in 3 publications, provided at 100 µg/ml
- raised against recombinant NOTCH2NL of human origin
- recommended for detection of NOTCH2NL of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NOTCH2NL Antibody (39-Y). This work is in progress.
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NOTCH2NL Antibody (39-Y) is a mouse monoclonal IgG1 kappa light chain antibody that detects NOTCH2NL protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-NOTCH2NL antibody (39-Y) is available as a non-conjugated format. NOTCH2NL protein, also known as Notch homolog 2 N-terminal-like, consists of 236 amino acids and plays a critical role in the Notch signaling pathway, which regulates cellular interactions that determine cell fate during development. This pathway influences processes such as cell differentiation, proliferation, and apoptosis in both embryonic development and adult tissue homeostasis. NOTCH2NL expression is observed in various tissues, indicating involvement in multiple signaling pathways, and dysregulation has been linked to several human tumors, where Notch proteins are often overexpressed or rearranged. Additionally, mutations in Notch genes, including NOTCH2NL, can lead to hyperplasia in the nervous system, highlighting NOTCH2NL′s importance in both normal physiology and disease states.
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NOTCH2NL Antibody (39-Y) References:
- Notch signaling: cell fate control and signal integration in development. | Artavanis-Tsakonas, S., et al. 1999. Science. 284: 770-6. PMID: 10221902
- Meningioma transcript profiles reveal deregulated Notch signaling pathway. | Cuevas, IC., et al. 2005. Cancer Res. 65: 5070-5. PMID: 15958550
- The molecular classification of multiple myeloma. | Zhan, F., et al. 2006. Blood. 108: 2020-8. PMID: 16728703
- Novel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach. | Birkaya, B., et al. 2007. BMC Mol Biol. 8: 43. PMID: 17521434
- Primers on molecular pathways--notch. | Lomberk, G. and Urrutia, R. 2008. Pancreatology. 8: 103-4. PMID: 18382095
- Notch1 is essential for postimplantation development in mice. | Swiatek, PJ., et al. 1994. Genes Dev. 8: 707-19. PMID: 7926761
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NOTCH2NL Antibody (39-Y) | sc-100307 | 100 µg/ml | $339.00 |