Date published: 2025-9-10

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Anticorps Notch 4 (C-3): sc-377399

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Fiches techniques
  • L'Anticorps Notch 4 (C-3) est un monoclonal de souris IgG3 κ, cité dans 2 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 3-31 près de N-terminus de Notch 4 d'origine mouse
  • recommandé pour la détection de Notch 4 d'origine mouse et rat par WB, IP, IF, IHC(P) et ELISA
  • Voir Notch 4 (A-12): sc-393893 pour d'autres anticorps conjugués Notch 4, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Notch 4 (C-3). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The LIN-12/Notch transmembrane receptors are believed to play a central role in development by regulating cell fate decisions. Four Notch homologs (Notch 1, Notch 2, Notch 3 and Notch 4) have been identified in mammals. The Notch genes are expressed in a variety of embryonic and adult tissues, suggesting that the genes are involved in multiple signaling pathways. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged1 can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. Jagged2 may be involved in tissue development that is dependent upon epithelial-mesenchymal interactions. In addition to its normal expression in the adrenal gland and placenta, Delta expression has also been found in neuroendocrine tumors.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps Notch 4 (C-3)

sc-377399
200 µg/ml
$316.00

Notch 4 (C-3) peptide neutralisant

sc-377399 P
100 µg/0.5 ml
$68.00

According to this datasheet, this NOTCH4 antibody (C3; sc-377399) is suitable for mouse or rat IHC. I'd like to ask you whether you've already tried this antibody for the human tissue IHC. If so, could you teach me the results for human?

Posée par: KIYOSHI
Thank you for your question. We have not yet confirmed reactivity of this specific Notch 4 antibody with human samples, and so it is not a recommended species reactivity for this clone at this time. This clone is specifically recommended for mouse and rat Notch 4. We do have a different Notch 4 antibody that is recommended for human, Notch 4 Antibody (A-12): sc-393893. However, this antibody has not yet been tested for IHC(P), or IHC on FFPE.
Répondue par: Technical Support
Date de publication: 2020-02-19

What application is the blocking peptide sc-377399 P appropriate for?

Posée par: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-02-27
  • y_2025, m_8, d_28, h_5CST
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Rated 5 de 5 de par CleanClean, robust band observed when used for immunoblotting mouse kidney tissue extracts. -SCBT QC
Date de publication: 2015-05-18
Rated 5 de 5 de par Exceptional immunofluorescence cytoplasmicExceptional immunofluorescence cytoplasmic staining in methanol-fixed NIH/3T3 cells. -SCBT QC
Date de publication: 2015-04-20
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Anticorps Notch 4 (C-3) est évalué 5.0 de 5 de 2.
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