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Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1), and NOR-1 (neuron-derived orphan receptor 1) constitute the NGFI-B subfamily within the nuclear receptor superfamily. Ligands for these protein have not been identified, and, therefore, they are designated "orphan nuclear receptors". Genes of the NGFI-B subfamily are classified as immediate-early genes, which are induced rapidly, but transiently, in response to a variety of stimuli. They have been implicated in cell proliferation, differentiation, and apoptosis. The human NOR-1 gene maps to chromosome 9q, and encodes a protein which is expressed in heart, skeletal muscle, thymus, and spleen as well as in brain, where it is developmentally regulated. There-fore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NOR-1 (F-10) | sc-393903 | 200 µg/ml | $316.00 | |||
NOR-1 (F-10): m-IgG Fc BP-HRP Kit | sc-538335 | 200 µg Ab; 10 µg BP | $354.00 | |||
NOR-1 (F-10): m-IgGκ BP-HRP Kit | sc-535924 | 200 µg Ab; 40 µg BP | $354.00 | |||
NOR-1 (F-10): m-IgG2a BP-HRP Kit | sc-548273 | 200 µg Ab; 10 µg BP | $354.00 | |||
NOR-1 (F-10) peptide neutralisant | sc-393903 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps NOR-1 (F-10) X | sc-393903 X | 200 µg/0.1 ml | $316.00 |