Date published: 2025-9-10

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Anticorps NG2 (F-12): sc-166179

5.0(1)
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Fiches techniques
  • L'Anticorps NG2 (F-12) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • soulevée à l'encontre des acides aminés 2023-2322 correspondant à C-terminus de NG2 d'origine human.
  • recommandé pour la détection de NG2 d'origine human par WB, IP, IF et ELISA
  • Voir NG2 (LHM 2): sc-53389 pour d'autres anticorps conjugués NG2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps NG2 (F-12) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps NG2 (F-12)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    NG2 (also known as melanoma-associated chondroitin sulfate proteoglycan 4, MCSP, MCSPG, MSK16 and MEL-CSPG) stabilizes cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. NG2 may facilitate primary melanoma progression by enhancing the activation of key signaling pathways important for tumor invasion and growth. Threonine 2256 phosphorylation of rat NG2 (Threonine 2252 phosphorylation of human NG2) leads to redistribution of NG2 on the surface of astrocytomas, polarization of the cell and a significant increase in cell motility. NG2 acts as a co-receptor for spreading and focal contact formation in association with α4 β1 integrin in malignant melanoma cells. NG2 is present on blood vessels throughout the rat embryo. Microvessels within the rat CNS express NG2 on endothelial cells, and outside the CNS, NG2 is present on smooth muscle cells. NG2 is a novel marker for epidermal stem cells that contributes to their patterned distribution by promoting stem cell clustering.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps NG2 (F-12)

    sc-166179
    200 µg/ml
    $316.00

    NG2 (F-12): m-IgG Fc BP-HRP Kit

    sc-537450
    200 µg Ab; 10 µg BP
    $354.00

    NG2 (F-12): m-IgGκ BP-HRP Kit

    sc-534722
    200 µg Ab; 40 µg BP
    $354.00

    NG2 (F-12): m-IgG2a BP-HRP Kit

    sc-548020
    200 µg Ab; 10 µg BP
    $354.00

    What is the recommended starting dilution for Western blot for sc-166179: NG2 (F-12) monoclonal antibody?

    Posée par: Professor Griffin
    The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Répondue par: Technical Support
    Date de publication: 2017-03-22
    • y_2025, m_9, d_9, h_6CST
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    Rated 5 de 5 de par Produced nice Western blot data of NG2 expressionProduced nice Western blot data of NG2 expression in SK-MEL-24 whole cell lysate. -SCBT QC
    Date de publication: 2014-02-03
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    Anticorps NG2 (F-12) est évalué 5.0 de 5 de 1.
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