NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NFATc4 (F-3) | sc-271091 | 200 µg/ml | $316.00 | |||
NFATc4 (F-3): m-IgG2b BP-HRP Kit | sc-548535 | 200 µg Ab; 10 µg BP | $354.00 | |||
Anticorps NFATc4 (F-3) X | sc-271091 X | 200 µg/0.1 ml | $316.00 |