Anticorps NASP (E-2): sc-398102
- L'Anticorps NASP (E-2) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 489-788 situés au niveau C-terminus de NASP d'origine human
- recommandé pour la détection de NASP d'origine mouse, rat et human par WB, IP, IF et ELISA
- Le m-IgG Fc BP-HRP et le m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps NASP (E-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps NASP (E-2)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Histones, the chief components of chromatin, are required for the formation of core nucleosomes around which DNA can wind and they play an essential role in DNA condensation and gene regulation. The transport of histones to the nucleus is crucial to ensuring proper nucleosome assembly and, ultimately, DNA replication. NASP (nuclear autoantigenic sperm protein) is a 788 amino acid protein that localizes to both the nucleus and the cytoplasm and contains three TPR repeats. Expressed as multiple alternatively-spliced isoforms, one of which is testis- and sperm-specific (tNASP) and the other expressed in somatic cells (sNASP), NASP functions as a Histone H1 binding protein that mediates histone transport to the nucleus and is required for normal cell cycle progression and cellular proliferation. Due to its testicular expression and important role in DNA replication and cell cycle events, NASP is necessary for spermatogenesis and normal development. Upon DNA damage, NASP may be phosphorylated by ATM or ATR.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NASP (E-2) | sc-398102 | 200 µg/ml | $316.00 | |||
NASP (E-2): m-IgG Fc BP-HRP Kit | sc-538365 | 200 µg Ab; 10 µg BP | $354.00 | |||
NASP (E-2): m-IgGκ BP-HRP Kit | sc-535965 | 200 µg Ab; 40 µg BP | $354.00 |