Date published: 2026-6-5

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n-Dodecyl α-D-maltoside (CAS 116183-64-3)

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CAS Number:
116183-64-3
Purity:
≥98%
Molecular Weight:
510.62
Molecular Formula:
C24H46O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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n-Dodecyl α-D-maltoside is a non-ionic detergent useful for solubilization, purification, and crystallography of membrane proteins as well as stabilizing and activating enzymes. n-Dodecyl α-D-maltoside has become a prominent compound in scientific research owing to its remarkable capability to solubilize proteins and macromolecules while preserving their native structure. Furthermore, it finds extensive application in the synthesis of diverse polymers and materials. Its utilization spans a broad spectrum of studies, including proteins, lipids, and nucleic acids, enabling investigations into cell membranes and delving into the intricate workings of enzymes. By providing a non-denaturing solubilization method, n-Dodecyl α-D-maltoside facilitates the examination of biological systems and enhances our understanding of their structure and function.


n-Dodecyl α-D-maltoside (CAS 116183-64-3) References

  1. Multiple types of association of photosystem II and its light-harvesting antenna in partially solubilized photosystem II membranes.  |  Boekema, EJ., et al. 1999. Biochemistry. 38: 2233-9. PMID: 10029515
  2. Green plant photosystem I binds light-harvesting complex I on one side of the complex.  |  Boekema, EJ., et al. 2001. Biochemistry. 40: 1029-36. PMID: 11170425
  3. The light-harvesting antenna of the diatom Phaeodactylum tricornutum. Evidence for a diadinoxanthin-binding subcomplex.  |  Guglielmi, G., et al. 2005. FEBS J. 272: 4339-48. PMID: 16128804
  4. Solubilization of green plant thylakoid membranes with n-dodecyl-alpha,D-maltoside. Implications for the structural organization of the Photosystem II, Photosystem I, ATP synthase and cytochrome b6 f complexes.  |  van Roon, H., et al. 2000. Photosynth Res. 64: 155-66. PMID: 16228454
  5. Photosystem II solubilizes as a monomer by mild detergent treatment of unstacked thylakoid membranes.  |  Dekker, JP., et al. 2002. Photosynth Res. 72: 203-10. PMID: 16228518
  6. Comparison of the α and β isomeric forms of the detergent n-dodecyl-D-maltoside for solubilizing photosynthetic complexes from pea thylakoid membranes.  |  Pagliano, C., et al. 2012. Biochim Biophys Acta. 1817: 1506-15. PMID: 22079201
  7. Proteomic characterization and three-dimensional electron microscopy study of PSII-LHCII supercomplexes from higher plants.  |  Pagliano, C., et al. 2014. Biochim Biophys Acta. 1837: 1454-62. PMID: 24246636
  8. Isolation of novel PSII-LHCII megacomplexes from pea plants characterized by a combination of proteomics and electron microscopy.  |  Albanese, P., et al. 2016. Photosynth Res. 130: 19-31. PMID: 26749480
  9. Structural variability of plant photosystem II megacomplexes in thylakoid membranes.  |  Nosek, L., et al. 2017. Plant J. 89: 104-111. PMID: 27598242
  10. Direct isolation of a functional violaxanthin cycle domain from thylakoid membranes of higher plants.  |  Goss, R., et al. 2017. Planta. 245: 793-806. PMID: 28025675
  11. A new, unquenched intermediate of LHCII.  |  Li, F., et al. 2021. J Biol Chem. 296: 100322. PMID: 33493515
  12. Isolation of fucoxanthin chlorophyll protein complexes of the centric diatom Thalassiosira pseudonana associated with the xanthophyll cycle enzyme diadinoxanthin de-epoxidase.  |  Goss, R., et al. 2023. IUBMB Life. 75: 66-76. PMID: 35557488
  13. Specific association of photosystem II and light-harvesting complex II in partially solubilized photosystem II membranes.  |  Boekema, EJ., et al. 1998. FEBS Lett. 424: 95-9. PMID: 9537522

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

n-Dodecyl α-D-maltoside, 1 g

sc-281069
1 g
$530.00