MS4A15 Antibody (C-9): sc-515078

MS4A15 Antibody (C-9) is a mouse monoclonal IgM antibody that detects MS4A15 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MS4A15 antibody (C-9) is available as the non-conjugated form. MS4A15 protein, a member of the membrane-spanning 4-domain family, subfamily A, is a 240 amino acid multi-pass membrane protein that plays a crucial role in various cellular processes. MS4A15 (C-9) antibody recognizes a protein involved in the regulation of immune responses and has been implicated in the modulation of calcium signaling pathways, which are essential for numerous cellular functions, including cell proliferation and differentiation. The gene encoding MS4A15 is located on human chromosome 11, a region associated with several genetic disorders, highlighting the importance of MS4A15 in maintaining cellular homeostasis and potential implications in disease mechanisms. Through interactions with other proteins in the MS4A family, MS4A15 may also contribute to the complex signaling networks that govern immune cell behavior, making MS4A15 a valuable target for research in immunology and related fields.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

MS4A15 Antibody (C-9) References:

1. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.  |  Ishibashi, K., et al. 2001. Gene. 264: 87-93. PMID: 11245982
2. Hereditary angioedema. Long-term follow-up of 88 patients. Experience of the Argentine Allergy and Immunology Institute.  |  Fabiani, JE., et al. 2000. Allergol Immunopathol (Madr). 28: 267-71. PMID: 11270087
3. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse.  |  Liang, Y. and Tedder, TF. 2001. Genomics. 72: 119-27. PMID: 11401424
4. Structural organization of the human MS4A gene cluster on Chromosome 11q12.  |  Liang, Y., et al. 2001. Immunogenetics. 53: 357-68. PMID: 11486273
5. Smith-Lemli-Opitz syndrome and the DHCR7 gene.  |  Jira, PE., et al. 2003. Ann Hum Genet. 67: 269-80. PMID: 12914579
6. The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease.  |  Schuchman, EH. 2007. J Inherit Metab Dis. 30: 654-63. PMID: 17632693
7. Jervell and Lange-Nielsen syndrome in Norwegian children: aspects around cochlear implantation, hearing, and balance.  |  Siem, G., et al. 2008. Ear Hear. 29: 261-9. PMID: 18595190
8. Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome).  |  Coldren, CD., et al. 2009. Neurogenetics. 10: 89-95. PMID: 18855024
9. An intronic mutation leading to incomplete skipping of exon-2 in KCNQ1 rescues hearing in Jervell and Lange-Nielsen syndrome.  |  Bhuiyan, ZA., et al. 2008. Prog Biophys Mol Biol. 98: 319-27. PMID: 19027783

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MS4A15 Antibody (C-9) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-MS4A15 Antibody (C-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MS4A15 Antibody (C-9) Specifications

Alternate Product Name: MS4A15

Product Clone Name: C-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 29-45

Epitope Target: MS4A15

Epitope Species: human

Product Reactivity/Detection: MS4A15

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for MS4A15 Antibody (C-9): P: Blocking Peptide