Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
ACCÈS RAPIDE AUX LIENS
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MOAP1 (modulator of apoptosis 1) is a 352 amino acid protein encoded by the human gene MOAP1. MOAP1 belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. When MOAP1 is associated with RASSF1, it promotes a Bax conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. MOAP1 is a homo-dimer and, under normal circumstances, is held in an inactive conformation by an intramolecular interaction. Binding to RASSF1 isoform A (RASSF1A) relieves this inhibitory interaction and allows further binding to Bax. MOAP1 will also bind to Bcl-2 and Bcl-x.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Are there any issues with using sc-130558: MOAP1 (MOAP-1-N) mouse monoclonal primary antibody on mouse samples?
Posée par: Dr Ninau Qelp
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-130558 conjugates.
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