Date published: 2025-9-7

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Anticorps MITF (4H205): sc-71587

4.3(3)
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Fiches techniques
  • L'anticorps MITF 4H205 est un monoclonal IgG1 de souris, cité dans 1 publications, fourni en 100 µg/ml
  • soulevée à l'encontre des acides aminés 408-419 MITF d'origine human.
  • recommandé pour la détection de MITF d'origine mouse, rat, human et avian et Xenopus par WB et IP; également réactif avec d'autres espèces, dont et equine, bovine and canine
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire MITF (4H205). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

MITF (microphthalmia-associated transcription factor) is a melanocytic nuclear protein that contains basic helix-loop-helix (HLH) and leucine zipper (LZ) domains. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. MITF can directly associate with DNA as a homodimer and is required for the development and differentiation of melanocytes. Its expression is upregulated by cAMP and cAMP-dependent pathways. MITF activates several different gene promoters by binding to their E-boxes. Tyrosinase, TRP1 and TRP2 are pigment synthesis genes activated by MITF. When MITF is phosphorylated on Ser73 (via the MAPK pathway), it associates with co-activators of the p300/CBP family and enhances transcription. MITF has several isoforms including MITF-M which is specifically expressed in melanocytes. In MITF-deficient mice there is a complete absence of melanocytes.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps MITF (4H205)

sc-71587
100 µg/ml
$316.00

Do you sell a small size of this MiTF Ab (sc-71587)?

Posée par: ND_WCM
Thank you for your question. No, we do not sell a smaller size. The smallest size available for this antibody is 100 ug in 1 ml. We do offer some free 10 ug sample sizes for alternative MITF antibodies, including: sc-515925, sc-52938 and sc-56726. Please contact our Technical Service Department for more information on how to receive a free 10 ug samples of monoclonal antibodies.
Répondue par: Technical Support
Date de publication: 2019-07-24

For Western Blot, is it recommended to use denatured or non-denatured conditions with MITF (4H205): sc-71587 antibody?

Posée par: Professor Griffin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Répondue par: Technical Support
Date de publication: 2017-03-27
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Rated 5 de 5 de par good results at correct molecular weightWe used this antibody for a western blot experiment and got nice dark bands in Jurkat cells at the correct molecular weight
Date de publication: 2017-01-19
Rated 3 de 5 de par Faint positive signal in western blot usingFaint positive signal in western blot using Jurkat whole cell lysates. -SCBT QC
Date de publication: 2015-05-27
Rated 5 de 5 de par StrongStrong, clean bands in western blot analysis of MITF expression in Jurkat and SK-MEL-28 nuclear extracts. -SCBT QC
Date de publication: 2014-03-08
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Anticorps MITF (4H205) est évalué 4.3 de 5 de 3.
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