Anticorps MIF (11): sc-130329
- L'Anticorps MIF (11) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 200 µg/ml
- dirigé contre la MIF recombinante d'origine human
- recommandé pour la détection de MIF d'origine human par WB, IP et ELISA
- Voir MIF (D-2): sc-271631 pour d'autres anticorps conjugués MIF, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- 2a BP-HRP">m-IgG2a BP-HRP est le réactif de détection secondaire préféré pour l'anticorps MIF (11) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps MIF (11)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor α (TNFα), interleukin-1 (IL-1) and interferon-γ (IFN-γ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MIF (11) | sc-130329 | 200 µg/ml | $316.00 | |||
MIF (11): m-IgG2a BP-HRP Kit | sc-546018 | 200 µg Ab; 10 µg BP | $354.00 |