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Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf82/MGC70857 gene product has been provisionally designated MGC70857 pending further characterization.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MGC70857 (G-9) | sc-365833 | 200 µg/ml | $316.00 | |||
MGC70857 (G-9): m-IgG2b BP-HRP Kit | sc-548561 | 200 µg Ab; 10 µg BP | $354.00 | |||
MGC70857 (G-9) peptide neutralisant | sc-365833 P | 100 µg/0.5 ml | $68.00 |