Date published: 2026-5-23

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Metosulam (CAS 139528-85-1)

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CAS Number:
139528-85-1
Molecular Weight:
418.26
Molecular Formula:
C14H13Cl2N5O4S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Metosulam functions by blocking the activity of acetolactate synthase (ALS), an enzyme for generating the amino acid valine required in protein biosynthesis. Through its ALS inhibiting properties, metosulam disturbs the plant′s regular growth mechanisms, resulting in the demise of the targeted weed. Its application extends to exploring herbicide effects on plants and investigating the impacts of plant growth regulators on overall plant growth and development. Furthermore, metosulam plays a significant role in studying plant-microbe interactions and examining weed control strategies.


Metosulam (CAS 139528-85-1) References

  1. Synthesis of the quinoline-linked triazolopyrimidine analogues and their interactions with the recombinant tobacco acetolactate synthase.  |  Namgoong, SK., et al. 1999. Biochem Biophys Res Commun. 258: 797-801. PMID: 10329466
  2. Development of an Enzyme-Linked Immunosorbent Assay for the Detection of Metosulam.  |  Parnell, JS. and Hall, JC. 1998. J Agric Food Chem. 46: 152-156. PMID: 10554211
  3. Determination of herbicides in mineral and stagnant waters at ng/L levels using capillary electrophoresis and UV detection combined with solid-phase extraction and sample stacking.  |  Hernández-Borges, J., et al. 2005. J Chromatogr A. 1070: 171-7. PMID: 15861801
  4. Analysis of triazolopyrimidine herbicides in soils using field-enhanced sample injection-coelectroosmotic capillary electrophoresis combined with solid-phase extraction.  |  Hernández-Borges, J., et al. 2005. J Chromatogr A. 1100: 236-42. PMID: 16212970
  5. Rapid analysis of triazolopyrimidine sulfoanilide herbicides in waters and soils by high-performance liquid chromatography with UV detection using a C18 monolithic column.  |  Rodriguez-Delgado, MA. and Hernández-Borges, J. 2007. J Sep Sci. 30: 8-14. PMID: 17313135
  6. A novel amino acid substitution Ala-122-Tyr in ALS confers high-level and broad resistance across ALS-inhibiting herbicides.  |  Han, H., et al. 2012. Pest Manag Sci. 68: 1164-70. PMID: 22431132
  7. Identification of the first glyphosate-resistant wild radish (Raphanus raphanistrum L.) populations.  |  Ashworth, MB., et al. 2014. Pest Manag Sci. 70: 1432-6. PMID: 24764154
  8. The MCRA toolbox of models and data to support chemical mixture risk assessment.  |  van der Voet, H., et al. 2020. Food Chem Toxicol. 138: 111185. PMID: 32058012
  9. Analysis of pesticide mixtures discharged to the lagoon of the Great Barrier Reef, Australia.  |  Warne, MSJ., et al. 2020. Environ Pollut. 265: 114088. PMID: 32531648
  10. Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads.  |  Low, YS., et al. 2021. Sci Rep. 11: 21055. PMID: 34702838

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Metosulam, 100 mg

sc-228603
100 mg
$400.00