In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med4 (mediator complex subunit 4), also known as ARC36, DRIP36 or VDRIP, is a 270 amino acid protein that localizes to the nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med4 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Med4 (D-7) | sc-398180 | 200 µg/ml | $316.00 | |||
Med4 (D-7): m-IgG Fc BP-HRP Kit | sc-538386 | 200 µg Ab; 10 µg BP | $354.00 | |||
Med4 (D-7): m-IgGκ BP-HRP Kit | sc-535992 | 200 µg Ab; 40 µg BP | $354.00 | |||
Med4 (D-7): m-IgG1 BP-HRP Kit | sc-545676 | 200 µg Ab; 20 µg BP | $354.00 |